Anti-inflammatory and antioxidant immunomodulatory effects of some natural common plants

AUTHORS:   A.M. Abdel-Mageed, Abdellatif, M. M, Ali Y. H, Doaa A. Elsayed, Intisar K.S and Medhat Ahmed Abu-Tahon

DOI10.5110/77. 1407               Page:   91-103          Vol: 19    Issue: 04   Year: 2024

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Immunity is the body’s defense system against infectious diseases. Many factors trigger an immune response including infections, immunization, and various external stimuli. In healthy organisms, the immune system maintains homeostasis within the body. The function and efficiency of the immune system are influenced by various exogenous and endogenous factors leading to either immunosuppression or immune stimulation; several agents that have activities to normalize or modulate the immune response are called immunomodulators. Due to the occurrence of chemical drug-related adverse effects such as drugs used as chemotherapy for treating different kinds of cancer, natural immunomodulators are the potential agents to replace them or even to reduce the severe side effects in the therapeutic regimens. The prevention and treatment of inflammatory diseases using natural bioactive compounds extracted from different natural sources have been reported in human history. The immunomodulatory characteristics of the natural bioactive compounds’ therapeutics have gathered the attention of researchers. Innovative technologies and promising research on the immunomodulatory effects of the bioactive compounds’ products extracted from different sources such as plants, fungi, or algae with immunomodulatory potential or/and anti-inflammatory, may enrich us with valuable entities to develop novel immunomodulatory agents to be involved in present chemotherapeutic strategies. Hence, in the current review, the immunomodulatory antioxidant and anti-inflammatory effects of some common plants have been shown.


Anti-inflammatory, antioxidant, immunomodulation, natural plants.

Received: 30 March 2024

Accepted:  11 April 2024

Published: 20 April 2024